At standard doses, most of the medication remains localized to vaginal tissue and produces minimal systemic hormone exposure
Pharmacological interventions may be appropriate if lifestyle measures prove insufficient
The primary impact, she explains, comes through rapid weight loss, which can affect hormonal balance and menstrual regularity
The findings may provide valuable information to aid the early identification of drug-related AP, and inform future studies on the pathogenesis of drug-induced AP
doi: 10.1038/s42255-023-00966-w 85 Amgen
457 Like atorvastatin, simvastatin slows MS progression by promoting Th2 cell differentiation while impeding Th1/Th17 cell function and the expression of IL-17, IL-22, and IL-21